Home Shop All The Best Probiotics in the USA: Backed by Science, Trusted by Healthcare Professionals

Very small things can make a real difference in your life. At Bio-K+, we believe your gut health is the foundation of your overall well+being, and we have spent more than 30 years making sure the science backs that up.

Bio-K+ brings you three proprietary, patented probiotic strains: Lacticaseibacillus casei LBC80R®, Lacticaseibacillus rhamnosus CLR2®, and Lactobacillus acidophilus CL1285®. These strains work in synergy to promote digestive and immune health,† and they are not available in any other product on the market.

Bio-K+ products are backed by 16 published clinical trials, 45+ peer-reviewed publications, and more than 30 years of probiotic research conducted in Laval, Quebec. CFU potency is guaranteed until the expiry date (whether 50 or 80 billion CFU), not just at the time of manufacture.

Browse our line of probiotics below and find the one made for your goals.

Why Bio-K+? A Science-First Probiotic Brand

The Science

L. casei LBC80R®, L. rhamnosus CLR2®, and L. acidophilus CL1285®. Three exclusive, patented strains backed by 16 clinical trials on the finished product, 45+ peer-reviewed publications, and 4 patent families. This is not a generic blend. This is a formula built on decades of research.

Quality Guarantee

CFU potency is guaranteed until expiry, not at time of manufacture. Every product is tested for bioactivity and gastrointestinal survival, so what’s on the label is what reaches your gut.

Formats for Every Need

From drinkable fermented probiotics that promote digestive and immune health from the first sip, to convenient shelf-stable capsules designed for an active lifestyle. Top probiotics meeting every routine, every schedule, every preference.

Drinkable or Capsule? Find Your Fit.

Not sure which format is right for you? Both options use the same three proprietary, patented probiotic strains and are backed by the same clinical evidence. The difference comes down to lifestyle.

Drinkable probiotics contain live and active bacteria that promote digestive and immune health† from the first sip, reaching both the upper and lower GI tract. Drinkables are ideal for those who want to make probiotics a part of their daily food ritual. Refrigeration is required.

Capsule probiotics use targeted-release technology that protects bacteria from stomach acidity and releases them in the intestines. Convenient and available in shelf-stable formats, capsules help support gastrointestinal health† and are practical for travel or on-the-go use.

Same strains. Same science. Choose what fits your life.

Frequently Asked Questions

What is the best probiotic?

Bio-K+ is formulated with three proprietary, patented strains and backed by 16 published clinical trials. Bio-K+ offers both drinkable formats that promote digestive and immune health† and capsule formats that help support gastrointestinal health.†

How is Bio-K+ different from other probiotic brands?

Bio-K+ is the only probiotic brand to use three synergistic, patented strains: L. casei LBC80R®, L. rhamnosus CLR2®, and L. acidophilus CL1285®. These strains are not available in any other product. Every drinkable bottle delivers 50 billion or more CFU guaranteed until the expiry date, and every product is developed and produced in-house in Laval, Quebec.

What are the structure-function claims for Bio-K+ probiotics?

Bio-K+ drinkable probiotics promote digestive and immune health.† Bio-K+ capsule products help support gastrointestinal health.† All claims are governed by FDA/DSHEA regulations.

How many CFUs should I look for in a probiotic?

CFU, or colony-forming units, indicates the number of live bacteria in each dose. Bio-K+ guarantees the stated CFU count on every product until the expiry date, not just at the time of manufacture. This distinction matters because many probiotics degrade over time. A guaranteed-until-expiry count means you receive the stated potency for the full shelf life of the product.

Which is better: drinkable probiotic or capsule?

Neither format is inherently superior. Both use Bio-K+’s three proprietary strains and are supported by the same clinical evidence. Drinkable probiotics contain live and active bacteria that promote digestive and immune health† from the first sip. Capsule probiotics help support gastrointestinal health† and offer the convenience of shelf-stable options for those on the go. The best choice depends on your lifestyle.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.