No. Bio-K+ On-the-Go Capsules are shelf-stable and do not require refrigeration. The bacterial count of 30 billion CFU per capsule is guaranteed until the expiration date at room temperature. A desiccant sachet in the bottle keeps the capsules dry and stable throughout your trip. They are safe to pack in carry-on or checked luggage. Unlike Bio-K+ drinkable probiotics, which must be refrigerated, the On-the-Go Capsules are specifically formulated for travel convenience.

Starting your probiotic routine a few days before departure gives the bacteria time to establish consistency in your gut before you encounter dietary changes or new environments. Continue taking one capsule daily throughout your trip and for at least a few days after returning, to support your gut as it readjusts to your regular routine. Take at the same time each day for best results.

Bio-K+ On-the-Go Capsules contain 30 billion live and active bacteria per capsule from three exclusive probiotic strains and are formulated to help support gastrointestinal health. Travel can disrupt the balance of intestinal flora through diet changes, stress, and exposure to new food environments. Daily probiotic support before, during, and after a journey is a practical step for supporting gut health while away. If you experience severe or persistent digestive symptoms, consult a healthcare professional.